Peptide growth factors combat scalp inflammation, which can disrupt hair growth. They also stimulate hair follicles and encourage the protein production necessary for healthy, strong hair. Studies indicate that using different growth factors together may be the most effective way of using them to treat hair loss.
sh-Oligopeptide-2, also known as Insulin-like growth factor 1 (IGF1), is a peptide produced in the human body. It tackles hair thinning by increasing the number of hair follicles and signalling follicle cells to stimulate hair growth. It also makes the hair shaft stronger and healthier, reducing shedding and breakage.
sh-Polypeptide-1, also known as Basic Fibroblast Growth Factor (bFGF), promotes circulation in the scalp and stimulates ‘resting’ hair follicles. This triggers them to enter the growth phase of the hair cycle and produce stronger hair.
sh-Polypeptide-9 or Vascular Endothelial Growth Factor (VEGF) stimulates blood capillary formation, allowing more nutrients and oxygen to be delivered to the hair follicles. This promotes hair growth and strength.
Copper Tripetide-1 improves circulation to the scalp and blocks the action of dihydrotestosterone (DHT), a hormone that restricts hair growth. It also prolongs the active phase of the hair growth cycle and enlarges hair follicles. These larger follicles produce thicker, stronger hair.
Vitamin C is necessary to produce collagen, a protein used in the structure of the hair, and it also increases the absorption of iron, which is an important nutrient for healthy hair. As an antioxidant, it can also help to combat oxidative stress caused by internal and external toxins such as alcohol and environmental pollution.
Vitamin A is used in the production of sebum, the oily substance that naturally moisturises your scalp and hair. Moisturised hair is less prone to splitting and less likely to be lost during styling. Vitamin A is also an antioxidant, helping to protect your hair from stresses such as UV light and pollution.
Vitamin B7 stimulates the production of keratin, another important protein in the hair structure. It also increases hair follicle growth.
Vitamin E is important for keeping the hair and scalp healthy and moisturised. There is some evidence that long-term supplementation can cause an increase in hair-growth, possibly due to Vitamin E’s antioxidant properties.
Vitamin B6 can improve hair condition and reduce hair loss by stimulating production of keratin and melanin (proteins found in the structure of the hair) and helping the amino acid cystine to form healthy new hair shafts. It also increases hair follicle density and can block dihydrotestosterone (DHT), a hormone that restricts hair growth.
Vitamin B1 is an antioxidant that can protect the hair from oxidative stress, which can make hair dry and brittle. It also promotes good blood circulation, essential for ensuring hair follicles get the nutrients they need.
Vitamin B12 deficiency is sometimes the cause of hair loss, either due to a health condition or insufficient quantities in the diet. B12 is vital to produce red cells, which in turn are crucial for carrying and delivering oxygen and iron to the scalp. Iron deficiency has been linked to hair loss.
Vitamin B2 deficiency is sometimes a factor in hair loss, possibly because of its key role in many of the processes necessary to grow healthy hair. It’s essential in the production of the protein collagen, which forms part of the hair structure, and for the production of glutathione, an important antioxidant. Vitamin B2 also helps in the circulation and delivery of iron and oxygen to the scalp.
Vitamin B3 reduces scalp inflammation and helps to build one of the hair structure proteins, keratin. It also improves blood flow and nutrient delivery to the hair follicles. Topical application has been shown to visibly improve hair fullness.
Vitamin B5 reduces scalp inflammation and keeps your scalp and hair moisturised by helping them lock in moisture. It can make the hair shaft fuller and more flexible.
Folic acid is key to healthy cell division and growth, and this includes hair follicle cells and oxygen-carrying, iron-rich red blood cells. It’s also an antioxidant, helping protect your hair from damage and aid in its repair.
Despite being known as Vitamin B8, Inositol isn’t a true vitamin but a vitamin-related sugar with important roles in the body, including signalling or ‘switching on’ cells. Inositol seems to be effective in treating hair loss triggered by sensitivity to dihydrotestosterone (DHT), a hormone that restricts hair growth.
Some amino acids are the protein building blocks that help to create the proteins in the hair shaft. Studies have shown that ammino acids can be absorbed into the hair from topical applications and have a measurable effect on hair strength, health and surface condition.
####Alanine
Alanine has anti-static properties, leaving hair less frizzy and tangled. This helps to reduce breakage and hair loss while brushing or styling.
Aminobutyric Acid stimulates cell growth and multiplication, making it vital for healthy hair follicle cells.
Arginine is necessary to produce nitric oxide, which acts to dilate blood vessels, thereby improving circulation to the scalp and stimulating hair growth. Arginine also provides a protective, moisturising coating for the hair shaft. This helps the hair withstand stresses from colouring, styling and the environment.
Like alanine, aspartic acid reduces the static charge of hair, leaving it smoother and so less prone to damage or loss during brushing or styling.
Cystine is an important building block for keratin and studies suggest it can signal hair follicles to move into the growth phase. It also has antioxidant properties, helping to combat oxidative stress caused by internal and external toxins such as alcohol and environmental pollution. Its base molecule, cysteine, has been shown to be effective in improving hair growth in small studies.
Glutamine delivers the essential sulphur that’s needed to grow healthy hair. Although glutamine is produced naturally in the body, the amount produced decreases with age, and in periods of stress.
Glutamic acid is the building block of glutamine, which delivers the sulphur necessary for hair growth. Studies have shown that topical applications of glutamic acid can increase hair growth in mammals.
Glycine reduces scalp irritation, moisturises the hair and scalp, and helps build the hair protein collagen.
Histidine has been shown to improve hair strength and to protect hair from damage caused by UV light (sun damage).
Hydroxyproline assists in the production of the hair protein collagen and has anti-static properties, helping to prevent tangling that can result in hair loss and breakage.
Isoleucine has anti-static properties and is important in building the potassium-ion channels in hair follicles, which are necessary for healthy hair growth.
Some studies have shown leucine deficiency to be a common factor in both men and women suffering from different types of hair loss, suggesting that leucine is vital to the hair growth process. Leucine is important in building the potassium-ion channels in hair follicles, which are necessary for healthy hair growth.
Lysine is primarily found in the root of the hair. It is involved in the formation of the hair protein collagen, and it also promotes healthy hair volume and shape. When paired with iron, Lysine has been shown to be effective in decreasing hair shedding in some people.
Methionine is another amino acid delivering sulphur to the scalp to create strong hair. It also provides an anti-static effect that can help reduce hair breakage and loss. Methionine is essential to the building of the hair protein collagen and is an antioxidant, helping to combat the effect of physical stresses on your hair. In combination with other amino acids and B vitamins, it’s been shown to help trigger and maintain the hair growth phase.
Ornithine is important in the growth and multiplication of hair follicles, and in the building of a healthy hair shaft.
Phenylalanine has been shown to increase the tensile strength of hair. Together with tyrosine, it builds melanin, the pigment responsible for hair colour.
Proline assists in the production of the hair protein collagen and has anti-static properties, helping to prevent tangling that can result in hair loss and breakage.
Serine is necessary to produce ceramides: fatty molecules which help to lock moisture into the skin and scalp. It also helps to replenish cysteine levels. Serine’s anti-static properties prevent tangling, helping to reduce breakage and hair loss.
Taurine protects the hair and hair follicle from transforming growth factor (TGF)-beta1, which can inhibit hair growth. It’s also used to produce the hair proteins keratin and collagen, and acts as an antioxidant, providing protection from stresses such as pollution. Taurine has an important role in ensuring nutrients such as sodium, potassium and magnesium pass into the hair.
Threonine is used to create glycine and serine, two other amino acids necessary for the production of collagen. It moisturises and nourishes the hair, and its anti-static properties help to prevent hair breakage and loss from tangling.
Tryptophan is necessary for the production of niacin (vitamin B3), which promotes circulation to the scalp and healthy hair growth. It also has anti-static properties that help to prevent hair breakage and loss from tangling.
Tyrosine works with phenylalanine to create melanin, which is the protein responsible for the colour in our hair. It’s also an antioxidant, helping protect the hair from stresses such as UV damage from sunlight.
Valine is important in building the potassium-ion channels in hair follicles, which are necessary for healthy hair growth.
Calcium aids the absorption of iron, which is vital for healthy hair growth. It also aids hormone and enzyme secretion, including the hormones and biotin enzymes that are involved in healthy hair growth.
Magnesium is essential for the building and healthy function of the cells that line hair follicles. It also has a role in building hair proteins and improving circulation to the scalp. Magnesium is vital in the control of calcium levels, helping to prevent the excess calcium build-up that can occur on the scalp when the skin is inflamed. Excess calcium can make the scalp dry and flaky, and clog hair follicles.
Potassium deficiency (hypokalaemia) can cause hair loss. Potassium is necessary for correct cell functioning and fluid balance in the body, including the scalp. It also regulates the hair’s pH balance and combats excess sodium build-up that can accumulate at the hair follicle. This sodium build-up can prevent nutrient uptake in the follicle.
Sodium chloride is a natural antiseptic and reduces scalp inflammation. It will also unclog follicles and manage sebum levels on the scalp. Sodium chloride can also reduce product build-up on the hair, helping to prevent breakage and hair loss when ‘sticky’ hair is brushed or styled.
Sodium phosphate is included in this formulation as a ‘buffer’; a substance that ensures the formulation remains at a healthy pH level for maximum efficacy and safety.
Coenzymes are organic compounds, often closely related to vitamins, that are necessary to help enzymes trigger essential chemical reactions in the body. These reactions help to create and release the nutrients and energy needed for healthy hair.
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